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NFL Series Records
Last 20 Years Arizona Cardinals vs San Francisco 49ers (49ers 21-20-0)
Click scores for game stats. Helmets courtesy The Helmet Project.
SeasonDateWeekAwayScoreHome
2024TBD18San Francisco 49ers  Arizona Cardinals
2024Sun
Oct 6, 2024
5Arizona Cardinals (48½)24-23San Francisco 49ers -7½
2023Sun
Dec 17, 2023
15San Francisco 49ers -12½45-29Arizona Cardinals (48)
2023Sun
Oct 1, 2023
4Arizona Cardinals (43½)16-35San Francisco 49ers -14
2022Sun
Jan 8, 2023
18Arizona Cardinals (39½)13-38San Francisco 49ers -14½
2022Mon
Nov 21, 2022
11San Francisco 49ers -8½38-10Arizona Cardinals (43½)
2021Sun
Nov 7, 2021
9Arizona Cardinals (45)31-17San Francisco 49ers -3½
2021Sun
Oct 10, 2021
5San Francisco 49ers (48½)10-17Arizona Cardinals -5½
2020Sat
Dec 26, 2020
16San Francisco 49ers (48½)20-12Arizona Cardinals -5
2020Sun
Sep 13, 2020
1Arizona Cardinals (48½)24-20San Francisco 49ers -7
2019Sun
Nov 17, 2019
11Arizona Cardinals (44)26-36San Francisco 49ers -10
2019Thu
Oct 31, 2019
9San Francisco 49ers -1028-25Arizona Cardinals (43)
2018Sun
Oct 28, 2018
8San Francisco 49ers -2½15-18Arizona Cardinals (40)
2018Sun
Oct 7, 2018
5Arizona Cardinals (40½)28-18San Francisco 49ers -3
2017Sun
Nov 5, 2017
9Arizona Cardinals -2½20-10San Francisco 49ers
2017Sun
Oct 1, 2017
4San Francisco 49ers15-18Arizona Cardinals -6½
2016Sun
Nov 13, 2016
10San Francisco 49ers20-23Arizona Cardinals 
2016Thu
Oct 6, 2016
5Arizona Cardinals 33-21San Francisco 49ers
2015Sun
Nov 29, 2015
12Arizona Cardinals 19-13San Francisco 49ers
2015Sun
Sep 27, 2015
3San Francisco 49ers 7-47Arizona Cardinals 
2014Sun
Dec 28, 2014
17Arizona Cardinals17-20San Francisco 49ers 
2014Sun
Sep 21, 2014
3San Francisco 49ers14-23Arizona Cardinals 
2013Sun
Dec 29, 2013
17San Francisco 49ers 23-20Arizona Cardinals
2013Sun
Oct 13, 2013
6Arizona Cardinals20-32San Francisco 49ers 
2012Sun
Dec 30, 2012
17Arizona Cardinals13-27San Francisco 49ers 
2012Mon
Oct 29, 2012
8San Francisco 49ers 24- 3Arizona Cardinals
2011Sun
Dec 11, 2011
14San Francisco 49ers19-21Arizona Cardinals 
2011Sun
Nov 20, 2011
11Arizona Cardinals 7-23San Francisco 49ers 
2010Sun
Jan 2, 2011
17Arizona Cardinals 7-38San Francisco 49ers 
2010Mon
Nov 29, 2010
12San Francisco 49ers 27- 6Arizona Cardinals
2009Mon
Dec 14, 2009
14Arizona Cardinals 9-24San Francisco 49ers 
2009Sun
Sep 13, 2009
1San Francisco 49ers 20-16Arizona Cardinals
2008Mon
Nov 10, 2008
10San Francisco 49ers24-29Arizona Cardinals 
2008Sun
Sep 7, 2008
1Arizona Cardinals 23-13San Francisco 49ers
2007Sun
Nov 25, 2007
12San Francisco 49ers 37-31Arizona Cardinals
2007Mon
Sep 10, 2007
1Arizona Cardinals17-20San Francisco 49ers 
2006Sun
Dec 24, 2006
16Arizona Cardinals 26-20San Francisco 49ers
2006Sun
Sep 10, 2006
1San Francisco 49ers (43½)27-34Arizona Cardinals -9½
2005Sun
Dec 4, 2005
13Arizona Cardinals 17-10San Francisco 49ers
2005Sun
Oct 2, 2005
4San Francisco 49ers14-31Arizona Cardinals 
2004Sun
Dec 12, 2004
14San Francisco 49ers 31-28Arizona Cardinals
2004Sun
Oct 10, 2004
5Arizona Cardinals28-31San Francisco 49ers